The Amazing Health Benefits of Papaya Seeds

PapayaPapaya is well-known for its amazing, nutritional, and medicinal properties throughout the world. The whole plant including its fruit, leaves, seed, root, bark, juice, and latex is used for nutrition, medicine, and various other health benefits.

Papaya can treat tumors with its physiochemical anticancer activities. Papaya is rich in enzymes and whole papain which is effective against cancer treatment.

Papain breaks down the fibrous cancer cell wall and turns protein into amino acid It also contains lycopene which is reactive towards oxygen and free radicals.

Isothiocyanate contained in papaya seed works well to help treat colon, breast, lung, leukemia, and prostate cancer. These enzymes are capable of preventing the formation and development of cancer cells.

The Amazing Health Benefits of Papaya Seeds

In a study, it was found that papaya seeds can guard against cancer. Papaya is well-known for its nutritional and medicinal properties throughout the world and is reported to have amazing health benefits.

The whole plant including its fruit, leaves, seed, root, bark, juice, and latex are ‘used for food, medicine, and various other purposes.Papaya Seeds

It has been shown that papaya can treat tumors due to its physiochemical which has anticancer properties. Some cancers are listed:-

  • Breast
  • Colon
  • Leukemia
  • Prostate.

Papaya is rich in the enzyme papain which is effective in fighting against cancer. Papain breaks down the fibrous cancer cell wall and protein turning them into amino acids.

Papaya also contains lycopene which is highly reactive toward oxygen and free radicals. There is Isothiocyanate contained in papaya seeds which works well to guard against these cancers.

What is Papaya

Papaya is from a small family of the Caricaceae which there are four genera in the world. The Carica papaya the most widely cultivated and the best-known
It is called many names (21) such as Papaya Melon tree, Pawpaw or Papau, Kapaya, Lapaya, Papayas, etc

Papaya is said to originate in southern Mexico and Costa Rica but is now grown across the globe for both home and commercial purposes.

Papaya has powerful anticancer properties and the seed extracts contain high levels of antibacterial activities.

In addition, the seeds of the unripe fruits are rich in benzyl isothiocyanate, a sulfur-containing compound that has been reported to be effective in germicide and insecticide. These compounds are important for plants’ natural defense mechanisms

A 2001study is reported that the medicinal uses of papaya seed have compounds that can treat the following conditions:-

  • flatulence,
  • anti-fertility drugs in males
  • counter skin irritation
  • treat ringworm
  • psoriasis
  • emmenagogue
  • vermifuge
  • liver cirrhosis
  • abortion.

It is also reported that seed juice is used for treating bleeding, piles, enlarged liver, and pectoral properties. In addition, the seed paste is used as an anthelmintic, and stimulates menstruation or is used as a drug for abortion.

The Anthelmintic Properties of Papaya Seeds

In a further study done in 2006, papaya seeds were approved for their effective anthelmintic properties against nematodes found in animals.

It has also been proven that the anti-fertility, anti-implantation, and abortifacient properties of papaya seed extracts have been established to possess potential anti-fertility drugs in males.

Studies done by the Health Journal of Pharmacognosy and Phytochemistry showed that when the unfermented extract of papaya seed was administered, the anthelmintic activity has been for the most part attributed to carpaine (an alkaloid) and carpasemine (benzyl thiourea).

Carpaine is suggested to have an intensively bitter taste and a strong depressant action It is present not only in papaya fruit and seed but also in its leaves.

Benzyl isothiocyanate (BITC), is identified as the main bioactive compound in papaya seeds and has been shown to be responsible for the anti-fertility effects

BITC is capable of damaging the endometrium, making the uterus non-receptive and, thus, affecting adversely the implantation process.

Papaya seeds are also a rich source of amino acids. The scented oil was extracted and used in the treatment of sickle cell disease, and poison-related disorders

Papain is used in various processes from food processing to dehair hides. Some functions are listed:-

  • to tenderize meat
  • clarify beers and juice
  • produce chewing gum
  • coagulate milk
  • prepare cereals
  • produce pet food
  • to treat wool and silk before dying, de-hair hides before tanningPapaya Tree with Green Fruits
  • adjust in rubber manufacturing

Papaya seeds are a rich source of amino acids, especially in the sarcotesta. This is characterized by a yellow to brown color with faintly scented oil which is extracted from the sun-dried, powdered seeds of unripe fruits.

The unripe (white) seeds yielded 16.1% oil while the ripe (black) seeds yielded 26.8% oil. It is believed that the oil might have edible and industrial uses.

Studies show that air-dried papaya seeds mixed with honey showed a significant effect on human intestinal parasites without significant side effects.
It was further shown that the consumption of papaya seed has a mono-therapeutic effect and can prevent intestinal parasitosis, especially in tropical communities.

The quality of seed production can become hampered by several limiting factors including physiological disorders.

Different nutrient deficiencies of boron, zinc, sulfur, and environmental stresses can cause physiological disorders such as bumpy fruits which may lead to deformed/discolored seeds.

Discolored seeds are known as vivipary seeds and the white seeds (disturbed sarcotesta) were identified as new physiological disorders of papaya under diverse agro-climatic conditions.

Effects On Cancer Treatment And Prevention

Papaya extracts are believed to may have altered the growth of several types of tumors. However, many studies focused on specific compounds in papaya and reported bioactivity including anticancer effects.

Further studies are still needed to confirm the report.

The use of papaya leaf tea is reported to have enzymes and high levels of cancer-fighting properties against a wide range of tumors, according to the Journal of Ethnopharmacology published on the 17th of February, 2010

Another important use of the papaya seed is believed to prevent or possibly treat food poisoning. The seeds of papaya are also believed to have strong anti-bacterial and anti-inflammatory effects on the digestive system.

Studies have shown that an extract made from papaya seed is effective in killing E.coli, Salmonella, Staphylococcus, and other bacterial infections.

There are even reports of using papaya seeds to successfully treat viral infections such as Dengue fever in parts of Central America like Costa Rica.

The Anti-amoebic activity

The study suggested that the cold macerated aqueous extract of matured papaya seeds (100 µ/mL) showed significant anti-amoebic activity against Entamoeba histolytica,

Anti-ulcer activity

Aqueous seed extract of papaya at the dose of 50 mg/ kg and 100 mg/kg against alcohol induced acute gastric damage and blood oxidative stress in rats.

The gastric acidity was significantly reduced in rats treated with 100 mg/kg of the extract


Papaya can treat tumors with its physiochemical anticancer activities and is rich in enzymes and whole papain which is effective against cancer treatment.

Papaya is a rich source of amino acids and the seed has strong antibacterial and anti-inflammatory effects. The seeds are also believed to successfully treat viral infections. Click here for more information.

I hope you find this article useful. If you have a question you can drop me a comment below and I will be more than happy to help you out.


5 thoughts on “The Amazing Health Benefits of Papaya Seeds”

  1. Hi Mazie,

    I too am a great admirer of papaya though I must admit that I did not know much about the benefits of papaya seeds.

    Papaya fruit is great for Liver and I always have at least one portion on most days of the week.

    How are the papaya seeds available in the market? Are they available in dried form or powdered.

    Definitely, will try that.



    • Hi Rohit,

      Thank you for your comment.

      The next time you fetch some Papaya, I’m suggesting you buy the whole fruit that way you can store the seeds.

      Try to dry them indoors as too much sunlight will destroy the integrity of the seed.  When they are dried you can do whatever to want to do with them.

      All the best.

    • Hi Rohit, 

      Thank you for your comment.  Papaya is a very great fruit.  There are so many things you can do with it.

      The next time you fetch your papaya, buy the whole fruit that way you can save the seeds for future use.  Dry them indoors and do not let them expose to too much sunlight, that way you preserve the integrity of the seeds.

      When they are dried you can do anything you want to do with them. 

      All the best.


  2. Hey much appreciate your post, Thankyou
    Believe it or not I haven’t tried papaya properly before however after reading your helpful on the amazing benefits this small fruit can bring, I definitely can’t miss out on it!
    Only thing is I’m wondering if this fruit is available the whole year or certain season, best check it out!

    Have a great day!

    • Hey Sariyah,

      Thank you for your comment.  Very much appreciated.

      depending on where on the globe you are, yes you can enjoy papaya all year round.  

      If you enjoy smoothies, papaya is a great fruit to add that way you can hydrate some papaya and store them in an airtight container and they keep for a very long time.

      Have a great one!


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